Model Customization

MingCelerKnockout

KO

Gene knockout mice (KO) are animal models developed through gene editing technology to completely remove a target gene from the genome, resulting in a total loss of its function. They are widely used in gene function research, disease mechanism investigation, and drug target validation.
MingCeler Biotech employs the TurboMice™ tetraploid complementation technique to construct gene knockout mice, enabling the generation of mice from cells in a single step.TurboMice™ technology breaks through the technical difficulties of long mouse modeling cycle and low success rate of complex models. It can realize the editing of almost any target gene locus.

Our advantages

01

3Rs benefit: no chimeras, no breeding selection required.
02

Targeted at a ‘Rosa26/H11’ locus;Reporter mice;Any target site you wish to knock in.
03

Humanizing multi-gene loci. Unrivaled speed and convenience.
04

With the ability to simultaneously edit multiple genes.

TurboMice™ Deliverables

End-to-End Services
Vector Design
ESC Editing
Tetraploid Complementation
Experiment-Ready Mice.

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Customized Genetic Models with Guaranteed Homozygosity—No Breeding Required

Guarantee

Mingceler provides the industry's most robust guarantee: successful generation of genetically engineered knockout mice. Should we fail to deliver animals with the specified genotype, the client’s service fee will be fully refunded*.

*Exclusions apply for genetic modifications that severely compromise viability, morbidity, or fertility due to intrinsic biological constraints.

Given the inherent complexity of biological systems, genetic modifications may not yield anticipated phenotypic outcomes. Mingceler’s guarantee strictly pertains to the development of animals possessing the genotype specified in the contract, with an accuracy of 100% at the DNA level, not the particular biological outcome, such as:

Gene transcription levels
Protein/RNA functionality
Organism-level biological phenotype

Online Quotation

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KO CKO KI CKI Humanize PM Transgenic IVF other
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5 10 20 other
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We offer tailored gene editing solutions—get a free quote instantly.
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Alternatively, call us at 400-8388-113 or reach technical support at 18126776342 (also available on WeChat).