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Why MingCeler
Why MingCeler
TurboMice™: Meet the Future of Mouse Model Creation
Making the UNTHINKABLE Real with TurboMice™
At Mingceler, we specialize in accelerating genetic research through our TurboMice™ technology, which harnesses optimized tetraploid complementation to deliver fully homozygous mouse models in just 2–4 months—60% faster than traditional breeding methods. Unlike conventional approaches that require 6–12 months of tedious breeding cycles, our process starts with precision editing of embryonic stem cells (ESCs) for targeted gene knockouts, floxing, or multi-locus modifications. We then use tetraploid complementation to develop these ESCs directly into experiment-ready mice, skipping the need for chimeric F1 and F2 generations. This method ensures 100% genotype certainty from the F0 generation, eliminating the guesswork of heterozygous screening and saving researchers thousands of hours spent on colony management.
TurboMice™ stands at the forefront ofnext-generation mouse model creation, providing unmatched efficiency andprecision in genetic engineering. By harnessing optimized tetraploid complementation technology, we offer researchers the ability to generate complex mouse models faster and more accurately than ever before. With theability to simultaneously edit multiple genes, TurboMice™ eliminates traditional bottlenecks like breeding and screening, dramatically reducing model development time. This revolutionary approachenables accelerated research and opens the door to more advanced and reliable scientific discoveries.
ES bank
MingCeler Mouse Custome
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TurboMice™ Knockout MiceHomozygous mice: 2~4 months
3Rs benefit: no chimeras, no breeding selection required.
Please Enter the number of Mice and Sex in the Requirements Section -
TurboMice™ Knock in Mice• Targeted at a ‘Rosa26/H11’ locus
• Reporter mice
Any target site you wish to knock in
Homozygous mice: 3~5 months
3Rs benefit: no chimeras, no breeding selection required.
Please Enter the number of Mice and Sex in the Requirements Section -
TurboMice™ Humanized Mice• Humanizing point mutations
• Humanizing domains, such as extracellular domains
• Humanizing the entire gene
• Humanizing multi-gene loci
Unrivaled speed and convenience
Homozygous mice: 3~5 months
3Rs benefit: no chimeras, no breeding selection required
Please Enter then umber of Mice and Sex in the Requirements Section -
TurboMice™ Conditional knockout MiceHomozygous mice: 4~6 months（Cre+fl/fl）
3Rs benefit: no chimeras, no breeding selection required
Please Enter thenumber of Mice and Sex in the Requirements Section
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TurboMice™ Point Mutant MiceHomozygous mice: 3~5 months
3Rs benefit: no chimeras, no breeding selection required
Please Enter thenumber of Mice and Sex in the Requirements Section -
TurboMice™ Multi-Site Gene Editing MiceHomozygous mice: 4~6 months
3Rs benefit: no chimeras, no breeding selection required
Please Enter thenumber of Mice and Sex in the Requirements Section -
TurboMice™ Transgenic MiceHomozygous mice: 3~5 months
3Rs benefit: no chimeras, no breeding selection required
Please Enter thenumber of Mice and Sex in the Requirements Section
Case Study
| Highly cooperative chimeric super-SOX induces naive pluripotency across species | Journal：Cell stem cell | IF=19.8 |
| Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation | Journal：National Science Review | IF=16.3 |
| Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models | Journal：Cell Research | IF=25.9 |
| SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target | Journal：Cell Research | IF=28.1 |
| Captopril alleviates lung inflammation in SARS-CoV-2-infected hypertensive mice | Journal：Zoological Research | IF=4.7 |
Online Quotation
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Fill out the form, and we will contact you within two business days.
Alternatively, call us at 400-8388-113 or reach technical support at 18126776342 (also available on WeChat).
